代表性论文:(*为通讯作者) 1. Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B. (2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron 37: 911-924. 2. Nishimura I, Yang Y, Lu B. (2004) PAR-1 kinase plays an initiator role in a multisite sequential phosphorylation process that confers Tau neurotoxicity in Drosophila CELL 116: 671. 3. Yang Y, Gehrke S, Haque M E, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S. Lu B(2005) Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci USA 102: 13670-13675. 4. Kumar S, Wen X, Yang Y, Buckmaster P. (2006) GABAA receptor-mediated IPSCs and α1 subunit expression are not reduced in the substantia nigra pars reticulata of gerbils with inherited epilepsy. J Neurophysiol 95: 2446. 5. Yang Y, Gehrke S, Imai Y, Huang Z, Ouyang Y, Wang JW, Yang L, Beal MF, Vogel H, Lu B. (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci USA 103: 10793-10798. 6. Yang Y, Ouyang L,Yang MF, Beal A, McQuibban H, Vogel B, Lu B. (2008) Pink1 regulates mitochondrial dynamics through interaction with fission/fusion machinery Proc Natl Acad Sci USA105:7070-75. 7. Yang Y*, Lu B. (2009) Mitochondrial morphogenesis, distribution and Parkinson’s disease: insights |